The opportunity

Current approaches to sequencing have only been able to provide insight to 1% of the full genome – until now.

One comprehensive test

From biopsy to an actionable report in clinically relevant timeframes, Isabl integrates data from 100% of the cancer DNA, germline DNA, and the transcriptome into a single diagnostic workflow. No more diagnostic odysseys.

Novel biomarker discovery

Comprehensive characterization of the genomic landscape across mutation classes removes any blind spots for biomarker development and identification of responder or non-responder subgroups.

Not just more data, better data

Isabl identifies all cancer associated mutations including mutations that no other cancer diagnostic assay can detect today, improving diagnosis for many patients.

The Isabl Difference

It's not just about having more data – it's about having the right data, delivered in the right format. Isabl looks at the whole picture – and delivers it in a clear and concise report to give you the information you need to provide truly personalized care to your patients.

Isabl GxT
Standard of care
Targeted RNA
Targeted DNA


Mutational Burden




Gene expression

Non-coding mutations

Rare cancer genes

Common cancer genes


Fusion genes

Copy number

Other biomarkers

Expression & Immunoprofiling

DNA small mutations

Structural changes


How our process works

Cancer diagnoses and prognoses are complex – but they don't have to be complicated. Isabl simplifies the process significantly, while providing incomparably clear, compelling results.

A sample is taken from the patient
The sample is then sequenced
We analyze & separate the important information
An accesible report is generated from the data

isabl for oncology

Informed research, evidence-led standards, better patient experience.

Isabl is collaborating with oncologists and cancer centers to evaluate clinical validity and utility across solid and heme cancer indications. Isabl GxT will be available for RUO release in Q2 2024. 
Now, we're looking for more partners to help continue our learning.

  • One comprehensive test from a single biopsy
  • Better risk stratification
  • End diagnostic odysseys
  • Improved treatment planning
  • Data driven treatment planning
  • Informed eligibility for clinical trials
  • Improved diagnosis

isabl for pharma

Decoding Cancer: Uncover Hidden Biomarkers, Enhance Drug Response.

Rare cancers, rare variants – Isabl’s FDA designated Breakthrough technology can help find patients with untapped biomarkers that might predict response.

  • Gain accurate mutation detection including gene mutations, allelic imbalances, structural variants, fusion genes, mutation signatures, TMB, MSI, HRD, and gene expression
  • Comprehensive assessment of clinical trial eligibility
  • Understand why some patients respond to a drug and why others don't

Isabl products

The most comprehensive WGS-based diagnostics.

With our strong scientific foundation and deep technical expertise, Isabl is at the forefront of WGS analysis. Our suite of products will set the course of future cancer care.

Isabl GxT Solid for solid tumors

Cancer whole genome and transcriptome and germline whole genome. Applied to Fresh Frozen (FF) and Formalin-fixed Paraffin Embedded (FFPE) samples with matched blood.

Isabl GxT Heme for hematological cancers

Cancer whole genome and transcriptome (no germline sample required). From blood and bone marrow (BM).

isabl´s core

We are a data-driven company working with advanced analytics.

With a strong scientific foundation, deep technical expertise, and using machine learning/AI to develop next generation biomarkers from WGS data, Isabl is creating one of the largest WGS datasets in the world that captures every relevant genetic biomarker now and in the future.

That means access to best-in-class genomic expertise.

Clinical cancer genomics has made great strides using targeted panels, but we are still missing what happens in 99% of the genome. Moving to whole genome and whole transcriptome sequencing will allow us to find all the key alterations in cancer genomes and help us identify more opportunities for patient tailored therapy.”

- Dr. Matthew Meyerson, MD, PhD